Mounjaro
(tirzepatide)
Once-weekly injection. The only dual-action GIP and GLP-1 treatment, with the strongest results seen in clinical trials — average weight loss of 20% or more at higher doses over 72 weeks. MHRA-licensed.
MHRA-Licensed · UK Prescribers · GPhC Pharmacy
GLP-1 Weight Loss Treatments
Weight loss treatment prescribed online by UK clinicians, with a free consultation and ongoing support.
- Weekly injections
- Daily tablets
- Clinician-led
- Ongoing support
GLP-1 medications work with your body's natural appetite hormones to reduce hunger and help you feel fuller for longer.
Choose between a once-weekly injection pen, where trial participants lost an average of 15% to 21% of their body weight, or a once-daily tablet, where participants lost an average of around 14%.* Your prescriber will recommend the option that best suits your health, lifestyle and preferences.
Complete a free online consultation and, if treatment is clinically appropriate for you, our GPhC-registered pharmacy team will dispense your medication with free, discreet next-day delivery and ongoing check-ins throughout your treatment.
Weekly injection
Average weight loss of 15% to 21%*
One injection a week using a simple pre-filled pen.
Daily tablet
Average weight loss of around 14%*
One tablet a day, taken in the morning on an empty stomach.
*Average weight loss in clinical trials of adults with obesity or overweight, when treatment was combined with a reduced-calorie diet and increased physical activity. The injection range covers semaglutide 2.4 mg (STEP 1, 14.9% at 68 weeks) and tirzepatide 5 mg to 15 mg (SURMOUNT-1, 15.0% to 20.9% at 72 weeks). The tablet figure is for oral semaglutide 25 mg (OASIS 4, 13.6% at 64 weeks). Individual results vary.
Why GLP-1's
Chart a healthier course with GLP-1
- 01GPhC-registered online pharmacy
- 02UK-licensed medication, dispensed from our own pharmacy
- 03Free, discreet, temperature-controlled next-day delivery
- 04Ongoing clinical support and dose reviews included
Understanding GLP-1
What are GLP-1 weight loss treatments?
GLP-1 (glucagon-like peptide-1) is a hormone your gut releases after eating. It tells your brain you're full, slows how quickly food leaves your stomach and helps regulate blood sugar. GLP-1 receptor agonist medications mimic this hormone — turning down hunger and food noise so that eating less feels sustainable rather than a daily battle of willpower.
The category has moved fast. Weekly injections such as Mounjaro (tirzepatide) and Wegovy (semaglutide) are now well established in the UK, and 2026 brought a landmark change: the MHRA approved Wegovy tablets — the UK's first once-daily GLP-1 weight loss pill — in June 2026, and Eli Lilly's rival tablet Foundayo (orforglipron), approved in the US in April 2026, is now MHRA-licensed too.
All GLP-1 weight loss treatments are prescription-only medicines. They are prescribed alongside a reduced-calorie diet and increased physical activity, following an online consultation reviewed by our prescribers to confirm the treatment is safe and appropriate for you.
Lose weight on your terms.
Real medication. Real doctors. No inflated prices. Just results.
New — MHRA approved June 2026
Wegovy Tablets
(oral semaglutide)
New for 2026. The UK's first once-daily GLP-1 weight loss tablet, MHRA-approved in June 2026. The same active ingredient as the Wegovy injection, with comparable weight loss in trials — no needles required.
Wegovy Injection
(semaglutide)
Once-weekly injection with an average 15% weight loss over 68 weeks in the STEP 1 trial, plus proven cardiovascular benefits in people with heart disease. One of the most widely prescribed weight loss treatments worldwide. MHRA-licensed.
New — MHRA-licensed
Foundayo
(orforglipron)
Eli Lilly's once-daily GLP-1 tablet, approved in the US in April 2026 and now licensed by the MHRA. It can be taken at any time of day, with or without food.
Nevolat
(liraglutide)
Once-daily injection. Branded Saxenda has been discontinued by Novo Nordisk, but generic liraglutide (Nevolat) contains the same medicine at the same dose and remains available for patients established on liraglutide or those it suits clinically.
Am I eligible for GLP-1 weight loss treatment?
GLP-1 weight loss treatments are licensed for adults who meet one of the following criteria, alongside a reduced-calorie diet and increased physical activity:
- A BMI of 30 kg/m² or above (obesity), or
- A BMI of 27 kg/m² or above (overweight) with at least one weight-related condition, such as type 2 diabetes, high blood pressure, high cholesterol, obstructive sleep apnoea or cardiovascular disease.
BMI thresholds may be adjusted for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean backgrounds, who are at higher cardiometabolic risk at lower BMIs.
Meeting the BMI criteria alone doesn't guarantee suitability — our prescribers review your full medical history. GLP-1 treatments are not suitable during pregnancy or breastfeeding, or for people with a personal or family history of medullary thyroid carcinoma or MEN 2, among other contraindications your prescriber will assess.
Weight loss treatment eligibility
- 1Basic Info
- 2Ethnic group
- 3Health conditions
- 4Results
Basic Info
What is your height?
What is your weight?
Full range
Compare GLP-1 weight loss treatments
*Results from separate clinical trials in different populations — trial results are not direct head-to-head comparisons. Individual results vary. Data: SURMOUNT-1 (tirzepatide), STEP 1 (semaglutide 2.4 mg), OASIS 4 (oral semaglutide 25 mg), ATTAIN programme (orforglipron), SCALE (liraglutide 3 mg).
Injections vs Tablets
Weight loss injections or weight loss tablets — which is right for me?
Until 2026, GLP-1 treatment in the UK meant an injection. That's changed. The choice now comes down to routine, preference and clinical suitability rather than efficacy alone:
Choose a weekly injection
Choose a weekly injection if you want a set-and-forget routine — one dose a week, no food timing rules. Mounjaro currently has the strongest trial results of any licensed weight loss treatment.
Choose a daily tablet
Choose a daily tablet if needles are a barrier. Wegovy tablets deliver injection-comparable weight loss but must be taken on an empty stomach each morning with a small amount of water, waiting at least 30 minutes before eating, drinking or taking other medicines — the routine matters for the tablet to work properly.
Your prescriber will help you decide during your consultation, and you can switch between formats later if your circumstances change — the MHRA has confirmed patients established on the 2.4 mg weekly Wegovy injection can move directly to the 25 mg daily tablet.
The Process
How to get GLP-1 weight loss treatment online
01
Complete your online consultation
A confidential health questionnaire covering your BMI, medical history and current medicines. Takes around 5 minutes.
02
Clinical review
A UK prescriber reviews your answers (and may request photo ID and full-body verification photos, in line with GPhC guidance for weight loss medicines) to confirm treatment is safe and appropriate.
03
Discreet delivery
If approved, your medication is dispensed by our GPhC-registered pharmacy and delivered free in temperature-controlled, unbranded packaging.
04
Ongoing support
Regular check-ins, dose escalation reviews and pharmacist access throughout your treatment — not just at the point of sale.
Your mission starts here
Lift off,
with the right support.
Dosage checks, ongoing care, and real support whenever you need it.
- Nutrition and exercise guidance
- Access to GLP-1 medications
- Dedicated care team
Wegovy tablets have landed
The first oral GLP-1 tablet — clinically proven weight loss, now available without a needle. Once daily, doctor-prescribed, delivered to your door.
Blame these people when you feel better
Extraordinary Specialists in medicine, nutrition, performance, and behavioural science.
Dr Aseel
Bedan
Medical Director, MBChB
Stefano
Mirabello
Pharmacist independent prescriber, MPharm, CSO
Amish
Patel
Pharmacist independent prescriber, BPharm
Navin
Khosla
Pharmacist independent prescriber, BPharm
Dr Jamie
Winn
Pharmacist, PharmD
Switching
Switching Treatments
Whether moving from an injection to needle-free, or stepping up from liraglutide — switching is straightforward with the right clinical guidance.
Switching from
Wegovy Injection
to
Wegovy Tablets
Same Molecule · No NeedleMHRA-confirmed: go directly from 2.4 mg injection to 25 mg tablet — no re-titration. Take first tablet up to 7 days after last injection dose.
Switching from
Mounjaro
to
Wegovy Tablets
Needle-Free SwitchIf you've achieved strong results on tirzepatide but want to eliminate injections, Wegovy tablets offer comparable efficacy without the needle — prescriber-planned transition required.
Switching from
Liraglutide / Nevolat
to
Wegovy Tablets
Upgrade · Oral OptionStep up from daily liraglutide injection to once-daily tablet semaglutide — superior efficacy (~13–14% vs ~6–8%), same daily dosing habit, no injection.
Switching protocol:
Never stop one GLP-1 and start another without prescriber guidance — timing of the crossover matters for safety and efficacy. Your From Mars prescriber will advise on the exact transition plan at your review consultation.
Safety & Side Effects
Are GLP-1 weight loss treatments safe?
Clinical track record
GLP-1 medications have been used clinically for nearly two decades — first in type 2 diabetes, and since 2015 in weight management — with a well-characterised safety profile. Like all medicines, they can cause side effects.
Common side effects
The most common are gastrointestinal — nausea, constipation, diarrhoea and vomiting — which are usually mild to moderate, most noticeable when starting treatment or increasing your dose, and tend to settle as your body adjusts. All GLP-1 treatments use gradual dose escalation to minimise this.
Important risks to know
Rarer but important risks include pancreatitis and gallbladder problems; seek urgent advice for severe, persistent abdominal pain. Women using oral contraception may need additional precautions when starting Mounjaro. Always tell your prescriber about all medicines you take, and read the Patient Information Leaflet supplied with your treatment.
Counterfeit warning
Only ever obtain GLP-1 medicines from a GPhC-registered pharmacy following a prescriber consultation. Counterfeit weight loss pens and unlicensed 'GLP-1' products sold via social media and unregulated websites are a serious and growing safety risk.
Side Effects
Full picture &how to manage them
Frequency
Side effects
What to do
Very common >1 in 10
Nausea, diarrhoea, constipation, vomiting
Cluster around dose steps and settle with time. Small bland meals, stay hydrated, avoid rich or fatty food during the adjustment window.
Common — up to 1 in 10
Reflux, bloating, burping, headache, fatigue, dizziness, hair shedding
Usually mild and transient; shedding relates to rapid loss and regrows
Uncommon
Gallstones, gallbladder inflammation, raised resting heart rate, hypoglycaemia (with diabetes medicines)
Report right-sided upper abdominal pain, fever or jaundice promptly
Rare but serious
Pancreatitis, severe allergic reaction (anaphylaxis), dehydration from prolonged vomiting
Severe persistent abdominal pain or facial/throat swelling: urgent medical help
The profile mirrors the weekly injection — same molecule, same class effects. Most side effects cluster around dose step-ups and settle within days. Tell any clinician before planned surgery or sedation that you take semaglutide, and report suspected side effects via the MHRA Yellow Card scheme.
Why From Mars
Why choose us
- 01
A real pharmacy, not a middleman
We are a GPhC-registered pharmacy dispensing UK-licensed medication from our own premises — no third-party fulfilment.
- 02
Clinician-led, always
Every order is reviewed by a UK prescriber, and every patient gets ongoing pharmacist support, dose reviews and side-effect guidance.
- 03
Cold-chain delivery done properly
Injectable GLP-1s are temperature-sensitive; ours ship in validated temperature-controlled packaging, free and next-day.
- 04
Honest clinical guidance
If a treatment isn't right for you, we'll say so — and if a newer option suits you better, we'll help you switch safely.
Houston,
we have answers.
Start strong. get £50 off your first month with frommars.
You can also cancel anytime, free of charge. Easy breezy.